Optitype hla分型结果
WebMay 20, 2024 · For both WES data and RNA-seq data, OptiType showed the highest accuracy for HLA-Ia typing than the other 3 programs at 2-digit and 4-digit resolution. Additionally, … WebNov 29, 2024 · Hi, Why I don't get HLA typing of all the genes (A, B and C) in a single run? Rather, I have to run multiple times to get that (as shown below). I wonder if its bug. And, do you think removing duplicate reads from input files (.bam) is w...
Optitype hla分型结果
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WebApr 25, 2024 · HLA分型. LOHHLA需要的输入文件中除bam外,还需要HLA Class I的分型结果以及肿瘤倍性与纯度信息。 其中HLA分型可使用Optitype、Polysolver、HLA-HD … Web一个常见应用:组织配型是器官或骨髓移植前最重要的检查之一,hla基因分型决定了移植器官与受者的基因相符程度,供者和受者hla相容性越高,排斥反应发生率越低,移植成功 …
WebJan 8, 2015 · HLA-I类基因分型软件-Optitype介绍. HLA(human leukocyte antigen ,人类白细胞抗原)是人类的主要组织相容性复合体(MHC)的表达产物。. 通常也称为人类主要组织相容性复合物 (MHC),在染色体 6p21.3 上包含一个 4 Mb 的区域,其中包含 200 多个基因。. HLA根据不同的基因位 ... WebOct 1, 2024 · For the individual loci, HLA-A, -B and -C, Optitype’s typing accuracy was the highest and HLA*LA had the highest typing accuracy for HLA-DRB1 and -DQB1. The tools’ robustness to lower DOC data ...
OptiType uses the following software and libraries: 1. Python 2.7 2. RazerS 3.4 3. SAMtools 1.2 4. HDF5 1.8.15 5. CPLEX 12.5or other Pyomo … See more Optional step zero: you might want to filter your sequencing data forHLA reads. Should you have to re-run OptiType multiple times on the same sample(different … See more OptiType is a novel HLA genotyping algorithm based on integer linearprogramming, capable of producing accurate 4-digit HLA genotyping predictionsfrom NGS data by simultaneously … See more WebDec 1, 2014 · To summarize, OptiType is a fast and accurate HLA typing method based on NGS data, which provides an alternative approach to common HLA genotyping methods. …
WebJun 14, 2024 · HLA(human leukocyte antigen ,人类白细胞抗原)是人类的主要组织相容性复合体(MHC)的表达产物,该系统是所知人体最复杂的多态系统。 HLA-I类分子:内源性 …
Weblinux-64 v1.3.2; noarch v1.3.5; conda install To install this package run one of the following: conda install -c bioconda optitype conda install -c "bioconda/label/cf202401" optitype camping in maine near oceanWebMar 7, 2024 · OptiType(2014年) —— 基于整数线性规划的HLA基因分型算法 [PMID: 25143287] xHLA (2024年) [PMID:28674023] (听说对硬件要求较高; HLA-HD (2024年) … first year expenses for a babyWebAug 20, 2014 · To summarize, OptiType is a fast and accurate HLA typing method based on NGS data, which provides an alternative approach to common HLA genotyping methods. It can be easily adapted to predict genotypes for loci other than HLA-I such as HLA-II and transporter associated with antigen processing. first-year experienceWebMay 20, 2024 · The accuracy of HLA-Ia typing by OptiType can reach 100% with the average depth of HLA gene regions >20x. Besides, the accuracy of 2-digit and 4-digit HLA-Ia typing based on control samples was higher than tumor tissues. In conclusion, OptiType by using WES data from control samples with the high average depth (>20x) of HLA gene regions … camping in manistee miWebJul 19, 2024 · HLAminer软件可以同时对HlA I型基因和II 型基因进行分型,但是分型结果中不可避免的会存在假阳性的结果。. 为了提高分型结果的准确性,不同的研究团队都在开发 … first year experience avcWebMay 31, 2024 · Precision HLA typing from next-generation sequencing data - Issues · FRED-2/OptiType. Precision HLA typing from next-generation sequencing data - Issues · FRED-2/OptiType. Skip to content Toggle navigation. Sign up Product Actions. Automate any workflow Packages. Host and manage packages Security. Find and fix vulnerabilities ... camping in maine old orchard beachWebOptiType. OptiType is an HLA genotyping algorithm based on linear integer programming. It provides accurate 4-digit HLA genotyping predictions from NGS data. For further reading and documentation see the OptiType documentation. The pipeline results contain a CSV file with the predicted HLA genotype. Each line contains one solution with the ... first year experience ccbc